Aquarius control SRX

Description

Delayed-release (enteric) coatings based on methacrylic acid-ethyl acrylate copolymer.

aquarius™ control SRX film coating systems are sustained-release coatings for APIs that are most effective when released over time. These film coating systems have predictable and controllable release retardation; are custom-formulated based on drug solubility and desired release profile; do not require a coalescence step and have stable dissolution profiles over a wide pH range. aquarius™ control film coating systems are durable, coherent coatings, in which film formation occurs via solvent evaporation – not latex coalescence – and film robustness is related to the use of a high-molecular weight polymer. They are solvent-dispersible ethylcellulose (EC) coatings for multiparticulates, potentially modified with hydroxypropylcellulose (HPC) as a pore former. They are available in several different porosities that can be matched to drug solubility and/or desired release profile. A key benefit of aquarius™ control SRX film coating systems is that they do not require curing after coating.

features and benefits:
o modified with hydroxypropyl cellulose or hydroxypropyl methyl cellulose as a pore former
o variable porosities can be matched to active pharmaceutical ingredient solubility and/or desired release profile
o suitable for moisture and heat sensitive actives
o do not require curing after application