CompactCel® SR

Product Information CompactCel® SR

BIOGRUND’s one-step matrix agent CompactCel® SR provides an easy-to-use compound which controls the sustained release of active ingredients. CompactCel® SR forms a gel, through which the active ingredient diffuses. The use of NaCMC accelerates the gel-forming process, so the initial drug release is reduced. The diffusion rate is affected by the cellulose ethers that are used. Mix- tures with high viscous compounds form a hard gel; mixtures with low viscous compounds form a light gel, so the drug release rate can be easily adjusted. CompactCel® SR can be used for direct compression and wet granula- tion. For direct compression, the active ingredient, excipients and CompactCel® SR should be mixed together in one step. For wet granulation, the active ingredient should be granulated first and then the granule (<400 μm) can easily be mixed with CompactCel® SR. BIOGRUND recommends using 10–30% within the tablet formulation.

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