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Gelucire 44/14

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Description

A nonionic water-dispersible surfactant for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble APIs. Self-emulsifies in aqueous media forming a fine dispersion, i.e., microemulsion (SMEDDS).

Solubilizer for poorly-soluble APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into microemulsion—LFCS Type III (SMEDDS). Wetting agent. Lipid binder in melt processes. Safety of use is inferred by extensive toxicological evaluations and precedence of use in approved pharmaceutical products.

Additional information

Manufacturer

Gattefosse

Quality

USP-NF/EP

Composition

small fraction of mono, di- and triglycerides and mainly PEG-32 (MW 1500) mono- and diesters of lauric acid (C12)

Dosage Form

Oral, Topical

Function

bioavailability enhancer, lipid binder, Solubilizer, Wetting Agent

Documents and Links

Brochure Gelucire® 44/14

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The Gelucire Family

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Brochure Oral Drug Delivery

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Product Catalogue

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