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GRANULAC 200

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Description

GranuLac® types consist of fine, sharp-edged lactose particles, having cohesive powder properties that can be beneficial during granulation processes. Clean unlubricated surfaces created during the compaction process as a result of brittle fracture lead to improved compactability.

MEGGLEs milled alpha-lactose monohydrate grades have been historically used as diluents in dry and wet granulation processes by numerous global and regional pharmaceutical manufacturers.

 

Standard Packaging:
25 kg – Paper bag with PE-EVOH-PE Inliner

Particle size distribution [Air jet sieve]

  • <32 µm: 45-75%
  • <100 µm: NLT 90%
Shelf life / Retest:
36 months

Typical Values

  • Bulk Density [g/l]: 530
  • Tapped Density [g/l] : 820
  • Hausner factor: 1.55
  • Carrs index: 35.37 %
Benefits
  • Good compactability
  • Narrow particle size distribution
  • Good blending properties
  • High storage stability
  • High batch-to-batch consistency

Areas of Application

  • Dry granulation
  • Wet granulation
  • Blends, premixes, sachets, triturations
  • Enhancement of flavours
  • Media for fermentation
  • Extrusion-spheronization

 

Granulac 200_Typical sizeParticle size distribution batch-to-batch consistency of GranuLac® 200 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Granulac 200_BatchParticle size distribution batch-to-batch consistency of GranuLac® 200 by air-jet-sieving.Data obtained from a permanent in-process-controll (IPC) of subsequent batches over a time period of 12 months.

Additional information

Manufacturer

Meggle

Quality

EP, JP, USP/NF

Cas-No

5989-81-1

Composition

Lactose Monohydrate

Dosage Form

Sachets, Tablets

Function

blends, Diluent for wet and dry granulation, extrusion spheronization, premixes, sachets and triturations

Documents and Links

Technical brochure Milled/sieved lactose

Download

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