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Klucel Xtend

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Description

Klucel™ Xtend HPC extended release matrix former is the new product in the Klucel™ line, offering unsurpassed process versatility and release profile efficiency. This step change product has been shown to match the release profile of widely used hypromellose controlled-release formulations with half the polymer concentration. Klucel™ xtend HPC is the only cellulosic excipient that provides a compendial extended release polymer option for hot-melt extrusion (HME).

Features:
o high gel strength
o low melt processing temperature
o process versatility

Benefits:
o consistent release profiles at lower concentrations than hydroxypropyl methylcellulose (HPMC)
o reduced burst effect in highly soluble APIs
o smaller tablets maximize capacity of plant equipment
o excellent performance in direct compression, wet granulation, dry granulation, and hot melt extrusion
o meets all compendia for HPC

Additional information

Manufacturer

Ashland

Quality

EP, JP, USP

Cas-No

9004-64-2

Composition

Hydroxypropyl cellulose (HPC)

Dosage Form

Tablets

Function

Sustained-release matrix

Documents and Links

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