Kolliphor® HS 15

Description

The potent nonionic solubilizer.

Kolliphor^® HS 15 is a potent non-ionic solubilizer and emulsifying agent, with low toxicity. Ideal for solubilizing low-solubility actives in microemulsions, it helps tackle even the toughest solubilization challenges. It is used for manufacturing aqueous parenteral preparations with vitamins A, D, E and K, plus lipophilic APIs such as propanidid, miconazole, alfadolone, alfaxalone, nifedipine, and piroxicam. Kolliphor^® HS 15 is soluble in water, ethanol, and 2-propanol. As a solubilizer, it is particularly suitable for parenteral and oral dosage forms, and lends itself well to veterinary formulations.

• Low histamine release, reduces side-effects
• Thermal stability, suitable for sterilization
• Lower hemolytic activity compared to other polyoxyethylene-based surfactants
• Monographed in Ph. Eur. and USP-NF