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Lauroglycol FCC

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Description

A nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms associated with skin penetration enhancement.

Main functionalities: Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulation. Safety of use is inferred by precedence of use in approved pharmaceutical products.

Additional information

Manufacturer

Gattefosse
Quality

USP-NF/EP
Composition

Consists of propylene glycol mono- and di- esters of lauric (C12) acid., Propylene glycol monolaurate (type I)
Dosage Form

microemulsion), Oral, Topical(Self-emulsifying lipid formulation for oral applications.Topical emulgel
Function

Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations, Solubilizer and cosurfactant for microemulsion in topical formulation, Solubilizer for poorly-soluble APIs and bioavailability enhancer.

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