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Plurol Oleique CC 497

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Description

A nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms.

Main functionalities: Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulations. Safety of use is inferred by precedence of use in approved pharmaceutical products.

Additional information

Manufacturer

Gattefosse
Quality

USP-NF/EP
Composition

Consists of polyglyceryl-3 esters of oelic acid (C18:1), the diester fraction being predominant., Polyglyceryl-3 dioleate NF, Polyglyceryl-3 oleate
Dosage Form

Topical
Function

Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations., Solubilizer and cosurfactant for microemulsion in topical formulations., Solubilizer for poorly-soluble APIs and bioavailability enhancer.

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