SEPISMART SR

SEPISMART™ SR is a ready-to-use excipient for sustained release tablet and capsule formulations.
It is a synergistic combination of natural co-processed gums, specially designed for Nutrition applications.

A valuable solution for food supplements

The sustained release technology allows the delivery of an effective amount of active ingredient over time and at a continuous rate.

Sustained release formulations offer a wide range of benefits including:

• Optimizing the dosage of active ingredients in the formulation
• Enhancing the absorption of nutrients with low bioavailability
• Providing high value solutions and marketing differentiation to formulators
• Avoiding any peak of active ingredients concentration with potential adverse effects
• Reducing number of intakes for the consumers and improving consumer compliance

Excellent sustained release properties

The carefully selected combination of natural gums allows SEPISMART™ SR to swell immediately in the presence of water and form a thick gel layer around the tablet.
As a result, the soluble active ingredients diffuse slowly through the gel layer whereas the insoluble ones are released gradually by tablet erosion.

Easy-to-use in direct compression

Thanks to the synergistic effect of the gums and the process used, SEPISMART™ SR is easy-to-use in direct compression.
SEPISMART™ SR has an excellent flowability and can be easily processed.
Tablets containing SEPISMART™ SR show excellent results in terms of hardness and friability at low compression forces.

Tablets formulated with SEPISMART™ SR in direct compression can then be coated if needed without altering the sustained release properties. It is fully compatible with:

• functional coating agents such as SEPIFILM™ LP when the active ingredient requires moisture protection
• aesthetic coating agents such as SEPIFILM NAT™ COL giving bright, stable and natural colors to the tablets

Release your creativity with SEPISMART™ SR

SEPISMART™ SR is your ideal solution to add a touch of innovation to your formulation. In addition to tablets, it can be used as it is:

• in hard capsules to bring a sustained release effect similar to the one observed in tablet form
• in granule form

Applications

SEPISMART™ SR  is fully compliant for use in Food Supplements in the EU and in the US.