VIVAPHARM® PVPP XL-10

Description

VIVAPHARM^® PVPP, Crospovidone, is unsurpassed in its performance and versatility as a superdisintegrant in formulations.

It combines different mechanisms to achieve rapid tablet disintegration at low concentrations (1-5%). Due to its viscoelasticity, VIVAPHARM^® PVPP is highly compactable, resulting in robust tablets with increased tensile strength and reduced friability. Scanning electron microscope images of VIVPHARM^® PVPP show a granular and porous structure with a large surface area. It enhances the dissolution of poorly soluble drug actives and due to its non-ionic property, it does not bear any risk of interaction with cationic APIs.

VIVAPHARM^® PVPP is available in two particle sizes to serve different application requirements.

Average Particle Size by Laser Diffraction [µm]: 30

Compendial Type: B

Benefits:

• Rapid disintegration at low concentrations (1-5%)
• Functions via a combination of disintegration mechanisms (wicking, shape recovery, and swelling), thus imparting its unsurpassed versatility as a superdisintegrant in formulations
• Suitability for use in direct compression, wet granulation, and dry granulation
• Increased tablet tensile strength and reduced friability due to high compressibility
• No gel formation even at higher concentrations (10%) – ideal for ODTs