Interpretable artificial neural networks for retrospective QbD of pharmaceutical tablet manufacturing based on a pilot-scale dev

Interpretable artificial neural networks for retrospective QbD of pharmaceutical tablet manufacturing based on a pilot-scale developmental dataset

26. January 2023

As the pharmaceutical industry increasingly adopts the Pharma 4.0. concept, there is a growing need to effectively predict the product...

Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for Paediatric Use

17. January 2023

Abstract One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and...

Quality by design approach with multivariate analysis and artificial neural network models to understand and control excipient variability

3. January 2023

Purpose Although understanding the variability in the physicochemical properties of an excipient in a drug formulation is becoming an important...

Optimized L-SNEDDS and Spray-Dried S-SNEDDS Using a Linked QbD-DM3 Rational Design for Model Compound Ketoprofen

1. January 2023

A QbD-DM3 strategy was used to design ketoprofen (KTF) optimized liquid (L-SNEDDS) and solid self-nanoemulsifying drug delivery systems (S-SNEDDS). Principal component...

Exposing Profound Screening Potential of Ethanol-Based Dissolution Media in the Development of Oral-Modified Dosage Forms

15. December 2022

Characterization of drug release from modified-release products in the presence of alcohol is required to evaluate the possibility of dose...

Pharmaceutical Hot Melt Extrusion Process Development Using QbD and Digital Twins

14. December 2022

Pharmaceutical product development guided by Quality by Design (QbD) is based on a complete understanding of the critical process parameters...

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach

4. December 2022

The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD)...

Development, Quality by Design-Based Optimization, and Stability Assessment of Oral Liquid Formulations Containing Baclofen for Hospital Use

25. November 2022

The absence of oral liquid pharmaceutical forms appropriate for use in pediatric and adult patients with difficulty swallowing is a...

Design And Optimization of Midazolam Loaded Microemulsion Using Quality by Design (Qbd) Assisted Statistical Modelling

20. November 2022

Abstract Introduction: More emphasize was given in the present work is application of QbD tools and DoE approach. The existing...

Itraconazole Amorphous Solid Dispersion Tablets: Formulation and Compaction Process Optimization Using Quality by Design Principles and Tools

17. November 2022

BCS Class II drugs, such as itraconazole (ITZ), exhibit poor solubility (1–4 ng/mL) and so require solubility enhancement. Therefore, ITZ...

Quality by Design (QbD)

Interpretable artificial neural networks for retrospective QbD of pharmaceutical tablet manufacturing based on a pilot-scale developmental dataset

Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for Paediatric Use

Quality by design approach with multivariate analysis and artificial neural network models to understand and control excipient variability

Optimized L-SNEDDS and Spray-Dried S-SNEDDS Using a Linked QbD-DM3 Rational Design for Model Compound Ketoprofen

Exposing Profound Screening Potential of Ethanol-Based Dissolution Media in the Development of Oral-Modified Dosage Forms

Pharmaceutical Hot Melt Extrusion Process Development Using QbD and Digital Twins

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach

Development, Quality by Design-Based Optimization, and Stability Assessment of Oral Liquid Formulations Containing Baclofen for Hospital Use

Design And Optimization of Midazolam Loaded Microemulsion Using Quality by Design (Qbd) Assisted Statistical Modelling

Itraconazole Amorphous Solid Dispersion Tablets: Formulation and Compaction Process Optimization Using Quality by Design Principles and Tools

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