Silica

Abstract Due to the poor solubility, permeability, stability and tumor-targeting ability of norcantharidin (NCTD), currently commercially available NCTD formulations require...

Abstract Mesoporous silica carriers are known to improve the solubility and bioavailability of poorly soluble Class II drugs. However, most...

In recent years, there has been much interest in three-dimensional (3D) printing for the development of personalized and on-demand medications...

Abstract The aim of this study was to investigate the feasibility of coated pellet formulation by high shear mixing of...

Abstract This study explores the potential of spectroscopic analysis combined with Partial Least Squares Regression (PLS) and Multivariate Curve Resolution-Alternating...

Abstract This study developed a solid self-nanoemulsifying drug delivery system (S-SNEDDS) to improve the oral bioavailability of poorly soluble carvedilol...

Abstract Purpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility...

Abstract Nanocapsules with core–shell structures hold significant potential across diverse applications. Biomimetic templating offers a benign approach for synthesizing inorganic...

Abstract Ibuprofen, one of the most widely used nonsteroidal anti-inflammatory drugs, is a poor-tasting and poorly soluble drug. As an...

Abstract Nowadays, most of the newly developed active pharmaceutical ingredients (APIs) consist of cohesive particles with a mean particle size...