Solid Dispersion

This study explores a novel acid-base supersolubilization (ABS) principle for enhancing the solubility and dissolution rate of indomethacin, a poorly...

Amorphous solid dispersions (ASDs) enhance the solubility and bioavailability of drugs, yet their inherent instability and the risk of recrystallisation...

Abstract Poor aqueous solubility and thereby poor and/or variable bioavailability of drug candidates is frequently overcome by developing enabling formulations...

Abstract Oral dosage is the most commonly used and preferred method of drug administration due to its several advantages, including...

Abstract Background/Objectives: Rutin, a bioactive flavonol glycoside known for its antioxidant, anti-inflammatory, and anticancer activities, faces limited clinical application due...

Abstract The limited aqueous solubility of numerous active pharmaceutical ingredients (APIs) remains a major barrier to achieving optimal oral bioavailability,...

Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems See the new book, edited...

Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems See the new book, edited...

Abstract Amorphous solid dispersions (ASD) are an effective strategy to enhance the solubility of poorly water-soluble drugs. Hot melt extrusion...

Abstract Pramipexole dihydrochloride (PPX) is a Biopharmaceutical Classification System (BCS) Class I drug with a short half-life, and its aqueous...