Solubilizer

Abstract Oral dosage is the most commonly used and preferred method of drug administration due to its several advantages, including...

  Lipid excipients offer a unique combination of benefits Poor solubility, poor permeability, and pre-systemic elimination are factors that can...

Skin, a gate to drug delivery Many approaches have been developed to overcome the skin barrier properties, including vehicledrug interactions,...

Abstract The excipient, Capryol® 90, comprises 90 % monoesters of propylene glycol monocaprylate (C8). With a low hydrophilic lipophilic balance...

Abstract Porphyrins, their derivatives, and metal ion complexes – particularly copper-substituted forms such as Cu-Chl, Cu-Chln, and Na-Cu-Chln – are...

Abstract For any drug to be therapeutically efficacious it must enter the systemic circulation and in order to do so,...

Abstract Introduction/Objectives Compounded pimobendan is prescribed without knowledge of the effect of excipients. The objective of this study was to...

Abstract Aqueous solubility is a crucial physicochemical property influencing drug absorption and bioavailability. Current solubility assays, whether assessing thermodynamic or...

Abstract Liver diseases—encompassing hepatitis, liver fibrosis, fatty liver, and hepatocellular carcinoma—constitute a formidable global health challenge. Existing treatments are often...

Abstract Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability....