Solubilizer

Abstract Porphyrins, their derivatives, and metal ion complexes – particularly copper-substituted forms such as Cu-Chl, Cu-Chln, and Na-Cu-Chln – are...

Abstract For any drug to be therapeutically efficacious it must enter the systemic circulation and in order to do so,...

Abstract Introduction/Objectives Compounded pimobendan is prescribed without knowledge of the effect of excipients. The objective of this study was to...

Abstract Aqueous solubility is a crucial physicochemical property influencing drug absorption and bioavailability. Current solubility assays, whether assessing thermodynamic or...

Abstract Liver diseases—encompassing hepatitis, liver fibrosis, fatty liver, and hepatocellular carcinoma—constitute a formidable global health challenge. Existing treatments are often...

Abstract Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability....

Abstract Tacrolimus (TAC), a calcineurin inhibitor used topically for T-cell-mediated skin diseases, faces challenges due to poor solubility and limited...

Abstract Pulmonary delivery can deliver cannabidiol (CBD) with high bioavailability and fast onset of action. One formulation obstacle is the...

Abstract Treating infected wounds is a major clinical challenge, and concerns about bacterial resistance have driven the shift toward natural...

Abstract This study investigates the intestinal permeability of solifenacin (SOL), a drug which is reported to have both hydrophilic and...