Solubilizer

Abstract Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability....

Abstract Tacrolimus (TAC), a calcineurin inhibitor used topically for T-cell-mediated skin diseases, faces challenges due to poor solubility and limited...

Abstract Pulmonary delivery can deliver cannabidiol (CBD) with high bioavailability and fast onset of action. One formulation obstacle is the...

Abstract Treating infected wounds is a major clinical challenge, and concerns about bacterial resistance have driven the shift toward natural...

Abstract This study investigates the intestinal permeability of solifenacin (SOL), a drug which is reported to have both hydrophilic and...

Abstract Currently, on-demand treatment of pain (both chronic and acute) is primarily achieved using opioids that are delivered systemically. Unfortunately,...

Dispersome is a solubility enhancement technology that relies on an innovative and naturally occurring excipient to develop amorphous solid dispersions...

Abstract Posaconazole (PCZ) is a broad spectrum anti-fungal drug approved by FDA and currently used off-label for the treatment of...

Abstract This study investigates the use of an octenylsuccinate-modified dendrimer-like biopolymer (OS-DLB) as a carrier matrix in the formulation of...

Abstract This study investigates the solubility and miscibility of ibuprofen (IBU) with four pharmaceutical polymers, KOLVA64®, KOL17PF®, HPMCAS, and Eudragit®...