Enhancement of saquinavir absorption and accumulation through the formation of solid drug nanoparticles

12. December 2018

Nanotechnology is now considered a promising drug delivery method for orally administered hydrophobic drugs to their sites of action. The...

Whey proteins as stabilizers in amorphous solid dispersions

9. December 2018

Whey proteins are extensively used as nutritional supplements but have so far not been investigated as co-formers for amorphous solid...

Dynamic Properties of Novel Excipient Suggest Mechanism for Improved Performance in Liquid Stabilization of Protein Biologics

3. December 2018

To improve liquid formulation stability, formulators employ various excipients designed to stabilize protein drugs, including buffers, salts, sugars, and surfactants....

The Coming of Age of Amorphous Solid Dispersions

29. November 2018

Although the majority of new drug candidates suffer from poor solubility and bioavailability, oral solid dosage forms remain the preferred...

Pharmaceutical preformulation studies and paediatric oral formulations of sodium dichloroacetate

20. November 2018

The purpose of this study was to develop liquid and solid paediatric formulations of sodium dichloroacetate (DCA) for the treatment...

Experimental process optimization approaches at spray drying of biopharmaceuticals

Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches

19. November 2018

Spray drying is increasingly becoming recognized as an efficient drying and formulation technique for pharmaceutical and biopharmaceutical processing. It offers...

Development of a Solid Supersaturated Self-Nanoemulsifying preconcentrate (S-superSNEP) of Fenofibrate using Dimethylacetamide and a Novel Co-processed Excipient.

18. November 2018

Recrystallization of drug and incomplete drug release from liquisolid formulation are two major hurdles in the development of a supersaturated...

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