Solubilizer

Natural compounds such as (−)-epicatechin show a variety of biological properties including anticancer activity. Nonetheless, (−)-epicatechin's therapeutic application is limited...

Soluplus is a pharmaceutical excipient used primarily in the manufacture of solid dispersions. The polymer also exhibits interesting rheology in...

We explore the impact of various polymers and their molecular weight on the stabilization of wet-milled suspensions of itraconazole (ITZ),...

We congratulate Merck for winning the Award with Parteck® MXP excipient for hot melt extrusion. Here some information on the...

The rate and extent of granule growth and densification during high-shear wet granulation (HSWG) depends on a variety of formulation...

The small intestine mucosal barrier is physiologically regulated by the luminal conditions, where intestinal factors, such as diet and luminal...

The formulation of amorphous solid dispersions (ASDs) is an effective way to improve the bioavailability of poorly water-soluble active pharmaceutical...

Usage of the amorphous phase of compounds has become the method of choice to overcome oral bioavailability problems related to...

The comparison of spray drying versus hot melt extrusion (HME) in order to formulate amorphous solid dispersions has been widely...

08. August 2018 Combinatorial chemistry, computational molecular modeling and high throughput screening in drug discovery have significantly increased the number...