Stabilizer

Abstract Cyclodextrins (CDs) are cyclic oligosaccharides made up of α-(1 → 4)-linked d-glucopyranose units and are generally obtained by enzymatic conversion of...

How moisture management, particle engineering, flowability, and grade selection can improve formulation performance and manufacturing consistency Introduction In pharmaceutical development,...

Abstract Protein-based therapeutics at high-concentrations often face significant development challenges, including high viscosity, limited solubility, poor injectability, and instability concerns....

Regulatory support for New Approach Methodologies is growing rapidly. For excipients, however, acceptance remains largely case-specific and linked to the...

Abstract Backgorund/Objectives: Respiratory diseases represent a substantial global health burden and require effective localised pulmonary delivery strategies, particularly for poorly water-soluble...

Abstract Madecassoside, a major triterpenoid glycoside from Centella asiatica, has potential value for dermatological applications; however, its poor stratum corneum permeability...

Abstract Objectives: Fixed-dose combination tablets containing sitagliptin hydrochloride (SG) and metformin hydrochloride (MF) are a mainstay in the clinical management...

Abstract Background/Objectives: The stability and biological safety of newly developed formulations must be established to support their therapeutic efficacy and...

Introduction In the realm of pharmaceutical formulations, excipients are indispensable, enhancing the safety, efficacy, stability, manufacturability, and patient acceptability of...

This article is part of the “Less Known Facts About Excipients” series by Philippe Tschopp. Gum Arabic Excipient: Origin, Structure,...