Stabilizer

Formulation Challenges in Low-Dose Fixed-Dose Combinations Developing fixed-dose combination (FDC) therapies presents unique formulation challenges, particularly when one active pharmaceutical...

Abstract Stabilization of therapeutic protein formulations with nonionic surfactants such as Polysorbate 20 (PS20), Polysorbate 80 (PS80), or Poloxamer 188...

Abstract Background/Objectives: Nanoemulsions (NEs) are a promising platform for transdermal drug delivery (TDD); however, how the polarity of the active pharmaceutical...

Abstract Mangiferin, a natural bioactive compound with multiple physiological functions, faces limitations in its oral bioavailability due to poor stability...

Abstract Effective dry-state stabilization of bacteriophages is crucial for expanding their therapeutic use. This study builds on previous findings that...

Abstract Lung-targeted drug delivery has emerged as one of the most promising strategies for treating lung cancer, enhancing local drug...

Abstract Hospital pharmacies are not equipped to produce lipid nanoemulsions, which are generally obtained using high-energy processes. This study reports...

Abstract Poor solubility of curcumin (Cur) has greatly limited its applications. To establish Cur amorphous solid dispersions (Cur ASDs) with...

Abstract Background/Objectives: Canagliflozin (CFZ) is the first sodium glucose co-transporter 2 (SGLT-2) inhibitor and is characterized by poor water solubility...

Abstract The glass stability of lyophilized amorphous peptide formulations, intended for incorporation into solid oral dosage forms, require stabilisation against...