Ashland

Abstract We investigated the microenvironmental pH (pHM)-modulating mechanism and intermolecular interaction of alkalizers and their impact on the aqueous stability,...

Abstract Objectives: A customizable 3D-bioprinted core-in-shell platform was developed for time-dependent oral colon delivery of live microorganisms. The system conveyed Lacticaseibacillus paracasei as...

Abstract Despite their widely recognized performance-related benefits, nanosuspensions (NSs) present major challenges, mainly due to their poor stability during storage....

WILMINGTON, Del., June 3, 2026, – Ashland, a global leader in specialty pharmaceutical excipients has announced the groundbreaking of a...

Abstract Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by...

Abstract Background/Objectives: For hyperlipidemic patients with statin resistance, a fixed-dose combination of a non-statin drug such as ezetimibe (EZT) and...

Abstract Objectives This study aims to investigate the effect of compaction pressure, coating polymer, pellet core, and spatial arrangement on...

Abstract This study aimed to develop strategies to prevent accelerated drug release (alcohol-induced dose dumping) from modified-release matrix tablets in...

Abstract The design of free-flowing lyophilized powders by spray-freeze-drying (SFD) enables novel therapeutic applications, including nasal administration. In this study,...

Abstract Hydroxypropyl methylcellulose acetate succinate (HPMCAS) is commonly used to develop amorphous solid dispersions (ASDs), but its use is mostly...