BASF

Abstract Background/Objectives: Poor aqueous solubility of active pharmaceutical ingredients (APIs) remains a critical barrier to effective oral formulation. This study...

Abstract Excipients are indispensable components of pharmaceutical dosage forms, significantly influencing product quality, safety, and performance. Conventional single excipients often...

Abstract Stabilization of therapeutic protein formulations with nonionic surfactants such as Polysorbate 20 (PS20), Polysorbate 80 (PS80), or Poloxamer 188...

Abstract Background/Objectives: Nanoemulsions (NEs) are a promising platform for transdermal drug delivery (TDD); however, how the polarity of the active pharmaceutical...

Abstract Tablet mechanical strength is governed by both the intrinsic mechanical properties of the constituent materials and the applied compaction...

Abstract Effective dry-state stabilization of bacteriophages is crucial for expanding their therapeutic use. This study builds on previous findings that...

Abstract The toxicological evaluation of excipients plays a crucial role in the development of SEDDS. This study examined key formulation...

Abstract Lung-targeted drug delivery has emerged as one of the most promising strategies for treating lung cancer, enhancing local drug...

Introduction Formulations comprising microcrystalline cellulose (MCC) are often used in wet granulation processes. In high shear wet granulation, MCC as...

Abstract Amorphous solid dispersion (ASD) is a widely adopted strategy to enhance the solubility of poorly water-soluble drugs. However, disintegration...