Beneo

Abstract Methods: Effervescent granules containing citric acid and sodium bicarbonate were successfully prepared for the first time via TS-MG using a polyol (sorbitol) as a melt binder. Results: Processing parameters, specifically granulation temperature and screw speed, were systematically…
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This poster was presented at the ECP 2025 in Porto Introduction Tablets are one of the most widely used oral dosage forms for oral delivery in the pharmaceutical and nutraceutical industries. If the drug dose per tablet is high and the formulation cannot ensure direct compression…
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This poster was presented at the ECP 2025 in Porto Introduction Polyols, such as mannitol, sorbitol, and isomalt, are widely used as excipients for tablet direct compression formulations because of their excellent compaction properties, flowability, as well as high and pH independent…
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Abstract The pharmaceutical industry is striving to develop innovative and promising tools, increasingly embracing new data-driven approaches, to understand, improve and accelerate the drug product development process. While extended release (ER) oral formulations offer a number of advantages,…
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Abstract Although the development of extended release (ER) matrices has been extensively investigated, understanding the most appropriate mechanism of drug release to achieve the desired release remains a cost- and time-consuming challenge in the early stages of formulation development. This study…
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Abstract The viability of probiotic microorganisms is essential for their health-promoting effects and must be preserved in the best possible way during the production of the final dosage form, such as tablets. This applies to both drying and tableting. Saccharomyces cerevisiae is spray-dried…
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This year´s CPHI Europe happend last week from 8th to 10th October  in Milano at Fiera Milano. . Pharma Excipients visited the excipients hall, hall 6 for you and in the following you find a broad range of booth photos as well as short introduction videos we recorded at CPhI 2024 in Milan. Here…
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This year CPHI Europe opens its doors in Milano at Fiera Milano. From 8th to 10th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE, MedTech and BioProduction will be held together with CPHI. Pharma Excipients gives you an overview…
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Abstract Poor water solubility is an important challenge in the development of oral patient-friendly solid dosage forms. This study aimed to prepare orodispersible tablets with solid dispersions of a poorly water-soluble drug fenofibrate and a co-processed excipient consisting of mesoporous silica…
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The increasing occurrence of highly potent or frequent-administration therapies in the drug development pipeline means that the low solubility of drugs is becoming a potential bottleneck for pharmaceutical formulators. This not only makes getting new medicines to market more time-consuming, it also…
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