Cyclolab

Abstract New oral tablets of nebivolol have been developed aiming to improve, by cyclodextrin (CD) complexation, its low solubility/dissolution properties—the...

The nasal administration route has been studied for the delivery of active molecules directed to the Central Nervous System, thanks...

Palbociclib (PAL) is an anti-cancer molecule that is highly selective for CDK4/6 inhibition and approved for the management of advanced...

Piperine (PP), a natural alkaloid found in black pepper, possesses significant bioactivities. However, its use in pharmaceutical applications is hindered...

The present study reports the effects of two pharmaceutical excipients of differing natures—non-ionic surfactant pluronic F127 (F127) and anionic sulfobutylether-β-cyclodextrin...

Abstract Amphiphilic cyclodextrin derivatives (ACD) are useful starting materials for nanomedicines; however, their synthesis using enzymatic catalysis is unsatisfactory. This...

Cyclodextrins (CD) and derivatives are functional excipients that can improve the bioavailability of numerous drugs. Because of their drug solubility...

We invite you to our next webinar: "Rational Selection of Cyclodextrins for the Solubilization of Poorly Soluble Oral Drugs"  ...

This study aimed to evaluate the effect of thiolated α-cyclodextrin (α-CD-SH) on the cellular uptake of its payload. For this...

The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE7-β-CD) on the bioavailability of valsartan....