Evonik

Abstract In pharmaceutical formulations, excipients are not inert additives but critical determinants of the solid-state properties, dissolution performance, and oral...

Abstract IBD (inflammatory bowel disease and colorectal cancer (CRC) are significant health challenges worldwide that are projected to rise substantially...

Abstract Porous silicates have been investigated as drug carriers to promote the solubility and in vitro dissolution of poorly water-soluble...

Abstract This study presents a Quality by Design (QbD) strategy combined with Design of Experiments (DoE) to develop hybrid polymer–lipid hot-melt extruded (HME) formulations...

Abstract Ellagitannins (ETs) from Punica granatum leaves are susceptible to degradation under less acidic pH conditions, which may compromise their use as...

Abstract Objectives: Fixed-dose combination tablets containing sitagliptin hydrochloride (SG) and metformin hydrochloride (MF) are a mainstay in the clinical management...

Abstract Hesperetin (HSP), a naturally occurring citrus flavanone with diverse antioxidant, anti-inflammatory, and pharmacological activities, has attracted considerable attention as...

Abstract Background/Objectives: Matrix pellet formulations enable homogeneous incorporation of the active ingredient and advanced control of release depending on the...

Abstract Background Phenytoin has long been used to accelerate wound healing. The aim of this study is to design, fabricate,...

Abstract Background: Hypertension exhibits marked circadian variations, with an increased risk of cardiovascular events during the early morning hours. Conventional...