Grace

Abstract This study aimed to address the challenges associated with the low oral bioavailability and the necessity for frequent dosing...

Abstract MUPS (multiple unit particle systems) are oral dosage forms consisting of small particles which are filled into capsules or...

Abstract Background/Objectives: Amorphization of an active pharmaceutical ingredient (API) can improve its dissolution and enhance bioavailability. Avoiding solvents for drug amorphization...

Abstract Mesoporous silica offers an easy way to transform liquids into solids, due to their high loading capacity for liquid...

Abstract Liquisolid systems (LS) represent a formulation approach where liquid drug or its dispersion is transformed into a powder with...

This poster was presented at the DDF Summit Conference 2024 by Valentyn MOHYLYUK, Zoltán Márk HORVÁTH, Kirils KUKULS, Liga LAUBERTE,...

Abstract Neratinib maleate (NM) used in the treatment of breast cancer, has a low and variable oral bioavailability due to...

Abstract Oral drug administration remains one of the most convenient routes due to its Simplicity, high patient compliance, and cost-effectiveness....

High-shear (HS) melt granulation and hot melt extrusion (HME) were compared as perspective melt-based technologies for preparation of amorphous solid...

Abstract Poor water solubility is an important challenge in the development of oral patient-friendly solid dosage forms. This study aimed...