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High-shear (HS) melt granulation and hot melt extrusion (HME) were compared as perspective melt-based technologies for preparation of amorphous solid...

Abstract Poor water solubility is an important challenge in the development of oral patient-friendly solid dosage forms. This study aimed...

Introduction Pellets are versatile dosage forms for many actives. To control drug dissolution profiles, they can be prepared with different...

Twin-screw melt granulation (TSMG) is one of the promising green technological approaches for the manufacturing of solid dosage forms of...

Abstract Amorphous solid dispersion (ASD) has emerged to be an outstanding strategy among multiple options available for improving solubility and...

Abstract The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim...

Abstract Aim: The present study was aimed at preparing stable dry adsorbed nanoparticles (DANs) of olanzapine (OLZ) loaded solid lipid...

Abstract The interest in Pickering emulsions is based on the possibility of replacing classical emulsifiers with solid particles. These emulsions...

Introduction Using in tablet formulations microcrystalline cellulose (MCC) with plastic behaviour and calcium phosphate anhydrous (CaHPO4 ) with brittle behaviour...

Introduction High-drug-loaded tablets and capsules are desirable and are manufactured using granulation as an additional step. Replacing batch wet granulation...