Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs

graphical abstract of Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs

Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs

20. January 2021

This study aims to examine the contribution of nanoporous silica entrapped lipid-drug complexes (NSCs) in improving the solubility and bioavailability...

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

14. January 2021

Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and...

graphical abstract of Development and statistical optimization of alginate-Neusilin US2 micro-composite beads to elicit gastric stability and sustained action of hesperidin

Development and statistical optimization of alginate-Neusilin US2 micro-composite beads to elicit gastric stability and sustained action of hesperidin

12. January 2021

The Alginate-Neusilin US2 micro-composite (MC) beads were fabricated and optimized for oral delivery of hesperidin (HES). A 32 full factorial design...

Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation

6. January 2021

Diacerein (DCN), a potent anti-inflammatory API used to treat osteoarthritis yet, it suffers from poor water solubility which affects its...

The evaluation of dynamic compaction analysis as a QbD tool for paediatric orodispersible mini tablet formulation

3. January 2021

The formulation of orodispersible minitablets (ODMTs) usually targets the disintegration time and mechanical strength, but should also consider a series...

$Roll Compactor with In-line laser diffraction to measure granule size$

Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width

22. December 2020

In continuous manufacturing of pharmaceuticals, dry granulation is of interest because of its large throughput capacity and energy efficiency. In...

graphical abstract of A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis

A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis

16. December 2020

Determination of the granule density as a critical quality attribute during roller compaction/dry granulation provides an important parameter for further...

multi-stage air classification roller compacted granules

A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis

15. December 2020

Determination of the granule density as a critical quality attribute during roller compaction/dry granulation provides an important parameter for further...

Pilot-scale high-speed electrospinning device with a continuous cyclone sample collector

Pharmaceutical applications of aqueous scaled-up electrospinning

14. December 2020

Thesis findings A solid formulation of a model biopharmaceutical drug (β-galactosidase) was developed and produced by high-speed electrospinning for the...

Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization

9. December 2020

Sulpiride (SUL) is a dopamine D2-receptor antagonist used for management of GIT disturbance and it has anti-psychotic activities based on...

JRS Pharma

Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

Development and statistical optimization of alginate-Neusilin US2 micro-composite beads to elicit gastric stability and sustained action of hesperidin

Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation

The evaluation of dynamic compaction analysis as a QbD tool for paediatric orodispersible mini tablet formulation

Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width

A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis

A novel approach to determine the granule density of milled ribbons using multi-stage air classification combined with dynamic image analysis

Pharmaceutical applications of aqueous scaled-up electrospinning

Enhancing the Low Oral Bioavailability of Sulpiride via Fast Orally Disintegrating Tablets: Formulation, Optimization and In Vivo Characterization

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