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Curcumin is a well-known phenolic compound obtained from Curcuma Longa L. It is used popularly as an antioxidant, anti-inflammatory, antispasmodic, antithrombotic, anticancer as well as immune-modulator. In the last couple of years, few studies showed the usefulness of curcumin against Helicobacter…
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To formulate and optimize Ozenoxacin nano-emulsion using Quality by Design (QbD) concept by means of Box–Behnken Design (BBD) and converting it to a gel to form Ozenoxacin nano-emulgel followed by physico-chemical, in-vitro, ex-vivo and in-vivo evaluation. This study demonstrates the application of…
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Abstract Nanocrystalline cellulose (CNC) has emerged as a subject of researcher’s interest because of its diverse attributes encompassing biocompatibility, sustainability, a high aspect ratio, and an abundance of −OH groups suitable for modifications. Sugarcane bagasse microcrystalline cellulose…
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Abstract Self-nanoemulsifying drug delivery systems (SNEDDS) have been used to improve the oral bioavailability of various drugs. In the current study, apigenin was developed as SNEDDS to solve its dissolution problem and enhance oral bioavailability and antioxidant potential. SNEDDS were…
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Breast cancer, the most common cancer among women, caused over 500,000 deaths in 2020. Conventional treatments are expensive and have severe side effects. Drug repurposing is a novel approach aiming to reposition clinically approved non-cancer drugs into newer cancer treatments. Atorvastatin calcium…
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Fouling reduces spray dryer operability. The impact of different configurations of a spray dryer on operability and nozzle-zone agglomeration stimulated by dry powder dosing was investigated through a combination of CFD simulations and pilot-scale experiments. Included were two positions of the…
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This year Vitafoods Europe opens its doors for the last time in Geneva at Palexpo. From 14th to 16th May you can have a face-to-face chat with visitors and exhibitors again. Pharma Excipients gives you an overview of the excipient suppliers, their booths, main topics and products in the…
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Abstract The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose personalisation and to improve patient compliance, as well as…
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Abstract Aim: The present study was aimed at preparing stable dry adsorbed nanoparticles (DANs) of olanzapine (OLZ) loaded solid lipid nanoparticles (SLNs) for sustained release. Materials/methods: OLZ SLNs were prepared by hot melt emulsification and ultrasonication using Precirol ATO 5 (PRE)…
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Shin-Etsu supplies the various excipients for pharmaceutical industry. Let us introduce you Shin-Etsu AQOAT® Hypromellose acetate succinate (HPMCAS, NF, JP), an enteric coating material that can be used in aqueous or organic media. Hypromellose is a non-toxic material which has been used in…
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