PMC Isochem

The physiological protective mechanisms of the eye reduce the bioavailability of topically administered drugs above all for those with high...

Purpose TXA9, a novel cardiac glycoside, has a potent anti-proliferative effect against A549 human lung cancer cells, however, possesses a...

Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used orally to manage HIV/AIDS infection. A pseudo one-solvent bottom-up approach was...

Raloxifene is commonly used for breast cancer protection. The low bioavailability of raloxifene (2%) is the result of its low...

Rapid advancement in drug discovery process is leading to a number of potential new drug candidates having excellent drug efficacy...

Disulfiram (DSF) is an FDA-approved drug that has been repurposed for cancer treatment. It showed excellent anticancer efficacy in combination...

Rationally designed combination nano-therapy approaches have emerged as a promising strategy for resistant breast cancer treatment. This research reports the...

Despite widespread use as an immunosuppressant, the therapeutic efficacy of the undecapeptide cyclosporine A (CyA) is compromised when given by...

Commercial development of nanosuspensions for oral drug delivery generally involves a drying step which aims to generate a stable product...

Raloxifene is commonly used for breast cancer protection. The low bioavailability of raloxifene (2%) is the result of its low...