Tag: formulation

Introduction to Enzyme‑cleavable Methadone Prodrugs Enzyme‑cleavable methadone prodrugs represent a novel class of pharmacological agents designed to provide controlled release ...

Oral Solid Dosage Forms (OSDFs) like tablets and capsules continue to serve as the cornerstone of pharmaceutical drug delivery, valued ...

Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid (Aβ) aggregation and limited treatment efficacy due to ...

Abstract Pharmaceutical cocrystals are a well-established class of solid-state forms that can modulate the solubility, dissolution, stability, and bioavailability of ...

Abstract Powder flow is a constant concern in the production of solid dosage forms. Its concise and reliable determination and ...

Abstract The glass stability of lyophilized amorphous peptide formulations, intended for incorporation into solid oral dosage forms, require stabilisation against ...

Abstract Low water solubility and extensive hepatic first-pass metabolism limit oral bioavailability of Nebivolol hydrochloride (NEB), a new-generation β-blocker agent ...

Abstract With great anticipation, the European Medicines Agency (EMA) guideline titled “Quality and Equivalence of Locally Applied, Locally Acting Cutaneous Products” officially ...

Dry Exfoliation Shampoo Cubes with HyPearls® Dry Exfoliating Shampoo Cubes combine hydration, exfoliation, and nourishment in one convenient format. They ...

Abstract Purpose Ustekinumab, targeting interleukin (IL)-12 and IL-23, is effective in treating chronic immune-mediated inflammatory diseases, but needs to be ...