lipid

The present study aimed to develop nanolipid carrier (NLC) loaded transdermal system of rivastigmine for bioavailability enhancement. NLC was optimized using Box-Behnken Design (BBD). Optimized formulation comprises oil (4% w/w), tween 80 (3% w/w) and span 80 (1.8% w/w) and was characterized. It…
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Partition coefficient (log P) is a key physicochemical characteristic of lipophilic drugs which plays a significant role in formulation development for oral administration. Lipid-based formulation strategies can increase lymphatic transport of these drugs and can enhance bioavailability many folds.…
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A very informative overview by Gattefossé on its excipients and uses thereof. Lipid excipients for suppository and pessary formulation include hard fat and hard fat with additives. These bases provide excellent physico-chemical stability and drug delivery properties covering a wide range of API,…
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