TPGS

Abstract Delamanid, an antituberculosis drug used for multidrug-resistant tuberculosis, has extremely poor water solubility and a high melting point of...

Abstract Insufficient aqueous dissolution properties constitute a fundamental barrier impacting approximately 40% of commercialized and 90% developmental pharmaceuticals, significantly limiting...

This year, the 15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology took place in Prague, Czech Republic. We show...

Abstract Colorectal cancer (CRC) continues to be a foremost human health concern globally, with chemotherapy being the cornerstone of the...

Abstract Therapeutic agents approved for the topical treatment of dermatological diseases have diverse physicochemical properties, but they are frequently poorly...

Abstract The aim of this study was to develop a once-daily controlled-release (CR) apixaban (APX) formulation that enhances bioavailability through...

Abstract Aims The objective of the present study was to develop and characterize tamoxifen (TAM)-loaded TPGS-PLGA nanoparticles (NPs) for more...

Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by β-amyloid (Aβ) aggregation and limited treatment efficacy due to...

Abstract Poor aqueous solubility and thereby poor and/or variable bioavailability of drug candidates is frequently overcome by developing enabling formulations...

Abstract A d-α-Tocopheryl Polyethylene Glycol-1000 Succinate (TPGS)-functionalized nanoparticle formulation was developed for the co-delivery of Paclitaxel (PTX) and Gefitinib (GEF)...