TPGS

Abstract The incorporation of poorly soluble active ingredients, which make up the majority of the molecules in development, into fixed-dose...

Abstract Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer lacking estrogen receptors, progesterone receptors, and HER2 expression,...

Abstract Aim: In addition to numerous benefits provided by nanosuspensions (NSs) (e.g., enhanced saturation solubility, increased area for interaction with fluids),...

Abstract Drug nanocrystals (NCs) have entirely changed the panorama of drug delivery, enabling enhanced drug absorption and long-acting drug release....

Abstract Aim Proteolysis targeting chimeras (PROTACs) exhibit a unique and promising pharmacology. However, this comes with molecular properties exceeding the...

Abstract Given the recurrent waves of COVID-19 and the emergence of new viral infections, optimizing the potential of remdesivir as...

Abstract Lung cancer, particularly NSCLC, poses a major therapeutic challenge due to drug resistance and the poor aqueous solubility of...

Abstract Background: D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS), an amphiphilic derivative of natural vitamin E, functions as both a drug efflux...

Abstract This study investigated the influence of solvent casting and hot-melt extrusion manufacturing methods on the physical, chemical, and functional...

Abstract Prostate cancer is the most common malignancy in men worldwide and docetaxel (DTX) is the treatment of choice. However,...