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Trehalose 100PH

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Description

Trehalose is a non-reducing disaccharide consisting of two glucose molecules linked by an α,α-1,1 bond. In nature, trehalose is a natural substance that stabilizes proteins, lipids, and carbohydrates during freeze-thaw or dehydration-rehydration cycles. Trehalose can mask unpleasant tastes and odors, improving the quality and acceptability of finished pharmaceuticals (dry syrups, liquid preparations, tablets and chewables). Trehalose enhances the stability of minerals (particularly magnesium and calcium) and increases their solubility. Due to its non-reducing end, trehalose does not react with amino acids and therefore contributes to their stability.

Trehalose 100PH: Trehalose 100PH is a highly purified trehalose without an endotoxin specification. Since it shows great benefit in masking unpleasant taste and odor, Trehalose 100PH can be used in syrup, dry syrup as well as chewable tablets, making it a more preferred additive for oral drug development.

Applications

  • Masking of unpleasant tastes and odors
  • Use as an excipient
  • Stabilization of biomaterials (proteins, etc.) during processing and storage

Additional information

Manufacturer

Nagase Viita

Composition

trehalose

Function

Additive for oral solutions, Excipient, Taste masking

Synonym

trehalose

Cas-No

99–20–7

Quality

EP, JP, USP/NF

Dosage Form

Oral

Technical Name

Trehalose

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