Abstract

In this study we present the use of co-axial electrospinning to produce core-shell composite micro-/nano- fibers of Polyurethane (PU) and Cellulose acetate phthalate (CAP). The designed fibers possess enhanced mechanical properties with a tensile strength of 13.27 ± 2.32 MPa, which is a clear improvement over the existing CAP fibers that suffer from a poor mechanical strength (0.2 ± 0.03 MPa). The CAP imparts pH responsiveness to the core-shell structure giving the fibers potential for “semen sensitive” (intravaginal) drug delivery.

More