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Abstract There is a growing demand in the subcutaneous delivery of monoclonal antibodies (mAbs) to reduce treatment burden for both...
Abstract In recent years, biologics-based modalities have increased significantly across various therapeutic areas. Monoclonal antibodies (mAbs) and emerging bioconjugates such...
Abstract The therapeutic landscape for biologics is rapidly transitioning from intravenous (IV) to subcutaneous (SC) administration, offering significant benefits in...
Abstract Building on growing evidence that ionizable lipids improve RNA delivery, in this work, we developed ionizable lipid/poly(lactic-co-glycolic acid) hybrid...
Abstract Preservatives are critical for preventing microbial contamination in multi-dose biologics, yet their compatibility with proteins poses a major challenge....
Abstract Macrophages, as cells of the innate immune response, are involved in the pathology of various medical conditions (tumors, intracellular...
Abstract The development of polymeric biomaterials for modern pharmaceutical formulations has attracted considerable attention, given the recent trend of advanced...
Abstract Oral delivery of peptides represents a promising alternative to invasive injectable therapies, offering improved patient adherence and convenience. Glucagon-like...
This poster has been presented at the 15th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, which took place in...
Abstract Contemporary small-molecule drug candidates increasingly have limited aqueous solubility, rendering oral delivery challenging. Amorphous solid dispersions (ASDs) and lipid-based...
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