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Abstract Background In the current era of the global increase in autoimmune and inflammatory disorders, predominantly rheumatoid arthritis (RA), there...
Abstract During the pandemic, lipid nanoparticles (LNPs) became widely established as RNA nanocarriers, and hold the promise of future targeting...
World’s First Mass Production Through Enzyme Innovation Trehalose (α-D-glucopyranosyl α-D-glucopyranoside) is a naturally occurring disaccharide prized for its ability to...
Abstract Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher target drug substance concentrations....
CPhI Frankfurt and AAPS PharmSci 360 Review Ashland showed multiple new and optimized pharmaceutical product offerings during CPHI Frankfurt and...
Abstract Cyclodextrins (CDs) have traditionally been recognized as excipients that enhance solubility and stability of drugs. However, growing evidence shows...
Abstract Biopharmaceutical medicines represent one of the most dynamic sectors of the pharmaceutical industry, with therapeutic proteins forming the largest...
Abstract Hybrid lipid nanocapsules (hLNCs) represent a promising platform for mRNA delivery with the added benefit of ambient-temperature stabilization. Conventional...
Abstract Surface adsorption of proteins in bulk drug product formulations and loss of protein structural integrity during manufacturing processes can...
Abstract Liver diseases—encompassing hepatitis, liver fibrosis, fatty liver, and hepatocellular carcinoma—constitute a formidable global health challenge. Existing treatments are often...
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