Pharma Excipients
Coating Systems and Additives
Tribology provides an in vitro tool that correlated to in vivo sensory data on the mouthfeel of…
Tribology is an emerging technique in the pharmaceutical field for texture and mouthfeel studies. Due to its relevance to oral sensory perception, tribology supports the development of novel products in the food industry. This study explores tribology as a tool to optimise the mouthfeel and ease of…
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Predictive Approach to Understand and Eliminate Tablet Breakage During Film Coating
Pharmaceutical tablets can be susceptible to damage such as edge chipping or erosion of the core during the tablet coating process. The intersection of certain process parameters, equipment design, and tablet properties may induce more significant tablet damage such as complete tablet fracture. In…
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Anti-counterfeiting protection, personalized medicines − development of 2D identification methods…
Counterfeiting of the products for healing is as old as trading, and it is difficult to quantify the magnitude of the problem. It is known that substandard and/or falsified (SF) medicines are a growing global threat to health, and they cause serious social and economic damage. The EU has a strong…
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EUDRACAP™ – The new platform of easy to handle capsules from Evonik
READY-TO-FILL COATED CAPSULES FOR FAST DRUG DEVELOPMENT
For pharmaceutical companies who are bringing a new oral drug product to market, the selection of the right coated capsule formulation can help to boost functional performance and accelerate speed to market. By leveraging more than 60 years of…
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Development of gastro-resistant coated probiotic granulates and evaluation of viability and release…
Probiotics have become one of the most consumed food supplements worldwide. Many probiotic strains are sensitive to low pH and bile concentrations encountered in the gastrointestinal tract upon oral ingestion. This study aimed at developing gastro-resistant probiotic granulates releasing viable…
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Biopolymer Coatings for Biomedical Applications
Biopolymer coatings exhibit outstanding potential in various biomedical applications, due to their flexible functionalization. In this review, we have discussed the latest developments in biopolymer coatings on various substrates and nanoparticles for improved tissue engineering and drug delivery…
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An Investigation into the Relationship between Xanthan Gum Film Coating Materials and Predicted…
Oral drug therapy is generally provided in the form of solid oral dosage forms (SODF) that have to be swallowed and move throughout the oro-esophageal system. Previous studies have provided evidence that the oro-esophageal transit of SODF depends on their shape, size, density, and surface…
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Better Medicines for Older Patients: Considerations between Patient Characteristics and Solid Oral…
Oral drug administration provided as solid oral dosage forms (SODF) remains the major route of drug therapy in primary and secondary care. There is clear evidence for a growing number of clinically relevant swallowing issues (e.g., dysphagia) in the older patient population, especially when…
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Investigating the influence of various plasticiser on the properties of Kollicoat® SR 30 D based…
INTRODUCTION
Plasticiser play a decisive role in the application of functional films, especially, if an aqueous dispersion containing a water insoluble polymer is used. For the water insoluble sustained release film forming polymer PVAc, both elongation at break and minimum film forming temperature…
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Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness,…
The feasibility of Optical Coherence Tomography (OCT) for in-line monitoring of pharmaceutical film coating processes has recently been demonstrated. OCT enables real-time acquisition of high-resolution cross-sectional images of coating layers and computation of coating thickness. In addition,…
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