Raman Spectroscopy as a PAT-Tool for Film-Coating Processes: In-Line Predictions Using one PLS Model for Different Cores

30. August 2020

Although Raman spectroscopy has been described as a potential process analytical technique for tablet coating, it has rarely been transferred...

Robustness Optimization of an Existing Tablet Coating Process Applying Retrospective Knowledge (rQbD) and Validation

13. August 2020

The objective of these studies is to verify and validate the improvement in the inter-tablet coating uniformity for an industrially...

In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations

14. July 2020

The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In...

Smart polymers for colon targeted drug delivery systems: a review

14. July 2020

The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug...

Mechanistic understanding of underperforming enteric coated products: Opportunities to add clinical relevance to the dissolution test

13. July 2020

Over the last 70 years several cases of in vivo failure of enteric coated (EC) formulations have been reported. The observed...

TABLET COATING: Discover Your Options And Avoid All Process Issues

29. June 2020

Have you missed this webcast on tablet coating by Seppic covering the following topics? Which coatings without TiO2? Which coatings...

Hot Melt Coating of Amorphous Carvedilol

11. June 2020

The use of amorphous drug delivery systems is an attractive approach to improve the bioavailability of low molecular weight drug...

Quality by Design (QbD) Approach to Match Tablet Glossiness

26. May 2020

A quality by design (QbD) approach was used for a PVA-based coating to develop a “look-alike” placebo tablet, which can...

Real-time monitoring of multi-layered film coating processes using Raman spectroscopy

25. May 2020

Raman spectroscopy was used as an in-line PAT tool to predict the applied coating mass of three different coating layers...

How to prepare a ready-to-use film coating suspension – a Video explanation

22. May 2020

Here is BIOGRUNDs step-by-step guide how to prepare a suspension. Equipment & Material Equipment: propeller stirrer, beaker Material: Water, AquaPolish...

Coating Systems and Additives