Process intensification of pharmaceutical powder blending at commercial throughputs by utilizing semi-continuous mini-blending

8. July 2024

Abstract Process intensification involves the miniaturization of equipment while retaining process throughput and performance. The pharmaceutical industry can benefit from...

The effect of material properties and process parameters on die filling at varying throughputs: A pls-model-based analysis

4. July 2024

Abstract When tablets are manufactured on a rotary tablet press and the throughput is increased, it leads to changes in...

Formulation Development and Evaluation of Cannabidiol Hot-Melt Extruded Solid Self-Emulsifying Drug Delivery System for Oral Applications

3. July 2024

Cannabidiol (CBD) is a highly lipophilic compound with poor oral bioavailability, due to poor aqueous solubility and extensive pre-systemic metabolism....

Real-time release testing of in vitro dissolution and blend uniformity in a continuous powder blending process by NIR spectroscopy and machine vision

29. June 2024

Abstract Continuous manufacturing is gaining increasing interest in the pharmaceutical industry, also requiring real-time and non-destructive quality monitoring. Multiple studies...

A review of hot melt extrusion technology

Implementation of an at-line nanoparticle size analyzer in a continuous nano-manufacturing line considering critical measurement and process conditions

24. May 2024

Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, 18 - 21 March 2024, Vienna, Austria:...

Continuous manufacturing