Continuous manufacturing

Abstract Continuous Manufacturing Technology continues to gain importance in pharmaceutical manufacturing. Although traditional processes like direct compression, roller compaction, or...

A model was developed for predicting the feed factor profile of a powder, processed through a gravimetric feeder, as a...

Residence-time-distribution (RTD)-based models are key to understanding the mixing dynamics of continuous manufacturing systems. Such models can allow for material...

This paper describes the specific control strategy of the commercial manufacturing process of an immediate release tablet formulation based on...

This study aimed at understanding the effect of screw design on the critical characteristics of granules and tablets of an...

In this study, a concentration predicting soft sensor was achieved based on the Residence Time Distribution (RTD) of an integrated,...

Various frameworks and methods, such as quality by design (QbD), real time release test (RTRT), and continuous process verification (CPV),...

Twin-screw extruders are useful in tuning certain product characteristics due to the ability to greatly modify screw profiles as well...

Continuous manufacturing (CM) sends materials directly and continuously to the next step of a process, eliminating hold times and reducing...

Techniques to overcome poor aqueous solubility of active pharmaceutical ingredients (APIs) continue to gain interest, with a reported 30% of...