DC excipient

Abstract In the present work, the application of lignin (LIG) as a bioactive additive for the preparation of drug-loaded tablets by direct compression has been studied, and its influence on the release of chlorzoxazone (CLZ) from the hydrophilic matrices has been followed. In hydrophilic matrices,…
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Roquette presents a new product: KLEPTOSE® F 7% - EXP β-cyclodextrin for oral dosage forms contains less than 7% of water. It is well suited for dry processing techniques, such as direct compression, where its low water content benefits moisture-sensitive APIs and formulations (e.g., ODTs,…
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Solidification of room temperature ionic liquids provides advantages in terms of handling and utilisation in the context of solid dosage forms. Encapsulating drug-based ionic liquids by direct spray operations represents a promising platform for solidifying and formulating these challenging…
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Abstract Process analytical technology (PAT) tools are an important part of process monitoring and control in pharmaceutical continuous manufacturing (CM) that help ensure product quality. However, there is hesitancy to adopt PAT due, in part, to the high start-up costs. A portion of the cost is…
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GANGWAL Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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Gangwal Healthcare Pvt. Ltd., part of the prestigious Gangwal Group, has been a pioneer in the Pharmaceutical industry since 1987. Driven by the sense of social wellbeing and the steely determination to make a difference through technology and expertise, Gangwal Healthcare continues to be at the…
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Abstract This study examines the influence of crospovidone (CP) manufacturer variability on the dissolution profiles of hydrochlorothiazide (HCTZ) tablets. Four CP batches from different manufacturers were characterized using pharmacopeial and physicochemical tests, including infrared absorption,…
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Introduction Super disintegrants are chemically modified version of traditional disintegrants used within tablets to improve the speed of release. The investigation looked at taking three commonly used super disintegrants (SSG, CCS and PVP) and incorporating into an Immediate release formulation.…
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Abstract Pediatric treatment of brain-related diseases often requires oral medications, where palatability is crucial for patient adherence and therapeutic success. The unpleasant taste of many drugs, especially those used in neurological or psychiatric conditions, can reduce compliance in…
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Abstract Process Analytical Technology (PAT) plays a crucial role in the design of today’s manufacturing lines as continuous manufacturing becomes more important. Until now PAT tools to measure the ribbon solid fraction (SFribbon) in-line are not commonly used in roll compaction. The aim of this…
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