Advancements in application of chitosan and cyclodextrins in biomedicine and pharmaceutics: recent progress and future trends

8. May 2024

Abstract The global community is faced with numerous health concerns such as cancer, cardiovascular and neurological diseases, diabetes, joint pain,...

Nanoparticles targeting the intestinal Fc receptor enhance intestinal cellular trafficking of semaglutide

25. January 2024

Semaglutide is the first oral glucagon-like peptide-1 (GLP-1) analog commercially available for the treatment of type 2 diabetes. In this work, semaglutide...

Design, development and scale up studies of metformin hydrochloride multiparticulate system: A promising alternative to large size tablet

23. January 2024

Metformin hydrochloride (MH) is prescribed for treating diabetes mellitus. The most popular dosage form, viz., tablets has a bulky nature...

Development of a multi-component gastroretentive expandable drug delivery system (GREDDS) for personalized administration of metformin

30. December 2023

Objectives Efficacy and compliance of type II diabetes treatment would greatly benefit from dosage forms providing controlled release of metformin...

Injectable systems for long-lasting insulin therapy

8. December 2023

Abstract Insulin therapy is the mainstay to treat diabetes characterizedd by hyperglycemia. However, its short half-life of only 4–6 min...

Figure 2. Endothermic curves of F1 (A), F2 (B), F3 (C), F4 (D), F5 (E), F6 (F), F7 (G) IDP, insulin (H), trehalose (I), inulin (J), poloxamer 188 (K), and HPMC E5 (L).

Stability study of spray freeze-dried insulin dry powder formulations used for nose-to-brain delivery

1. November 2023

Insulin is classified as a cold chain product due to being a peptide hormone with stability issues in the liquid...

Fig. 1. The theoretic advantage of oral insulin versus subcutaneous (SC) injection [8]

A Shrewd Ingenious Approach of Oral Drug Delivery of Insulin for the Amelioration of Diabetic Patients with Better Therapeutic Outcomes

27. October 2023

Since 1922, insulin has saved the lives of countless people. However, the difficulties of subcutaneous administration, the need for frequent...

Diabetes