Film forming systems for topical and transdermal drug delivery

31. August 2020

Methyl ester derivatives of alginic acid have been evaluated as potential multifunctional excipients for pharmaceutical direct compression. The use of...

Evaluating drug distribution and release in ophthalmic emulsions: Impact of release conditions

24. August 2020

The purpose of this study is to investigate the process of drug distribution and mechanism of drug release of ophthalmic...

Microemulsion assisted transdermal delivery of a hydrophilic anti-osteoporotic drug: Formulation, in vivo pharmacokinetic studies, in vitro cell osteogenic activity

17. August 2020

Gastrointestinal adverse effects such as esophageal irritation and ulcers are the major disadvantages of the oral administration of alendronate (ALD)...

A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies

31. July 2020

The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the...

Major biological activities of essential oils

Essential oils: a review on their salient biological activities and major delivery strategies

10. July 2020

Essential oils are volatile, complex products of plants as secondary metabolites and include terpenes and their oxygenated derivatives, such as...

Hierarchical mesoporous silica templated by the combination of fine emulsion and micelles

17. June 2020

Highlights • Mixed Organized Molecular Systems are formed by the mixture of Kolliphor and P123 templates. • Hierarchical mesoporous silicas...

Percutaneous delivery of levetiracetam as an alternative to topical nonsteroidal anti-inflammatory drugs: formulation development, in vitro and in vivo characterization

2. June 2020

The study focused on formulation of carmellose sodium hydrogels and nonionic microemulsions with 5% and 10% of levetiracetam and investigation...

Residual film formation after emulsion application: understanding the role and fate of excipients on skin surface

2. June 2020

This study focuses on the fate of excipients contained in topical emulsions once applied on the skin. The aim was...

Enhancing in vivo oral bioavailability of cajaninstilbene acid using UDP-glucuronosyl transferase inhibitory excipient containing self-microemulsion

5. May 2020

Cajaninstilbene acid (CSA) exerts wide pharmacological activities, such as anti-inflammation, hypoglycaemic activity, analgesic effect and cognition improvement. However, it underwent...

Pickering nano-emulsions stabilized by Eudragit RL100 nanoparticles as oral drug delivery system for poorly soluble drugs

24. April 2020

The purpose of this study was to develop Pickering water-in-oil nano-emulsions only stabilized by Eudragit RL100 nanoparticles (NPs), in order...

Emulsifier