Engineering oral delivery of hydrophobic bioactives in real-world scenarios

21. April 2020

Bioactive compounds, often hydrophobic in nature, tend to degrade during processing outside or inside the body with rapid clearance rates,...

Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS) for Combined Oral Delivery of Curcumin and Piperine

15. April 2020

Abstract Background: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. Objective: To design...

Development and Optimization of Self-nanoemulsifying Drug Delivery System of Ibrutinib

3. April 2020

Objective: The present research demonstrates the formulation of novel self-nanoemulsifying drug delivery system (SNEDDS) for potential delivery of ibrutinib by...

different geaphs about darunavir solubilizers

Design and Development of Darunavir Loaded Self Micro Emulsifying Drug Delivery System using Extreme Vertices Mixture Design in a Quality by Design Framework

17. March 2020

The therapeutic utility of many poorly water-soluble drugs are severely restricted for their bioavailability. The present study was aimed to...

Development and Characterization of Water-in-Oil Microemulsion for Transdermal Delivery of Eperisone Hydrochloride

13. March 2020

Background: Eperisone hydrochloride possesses short biological half-life due to first pass metabolism resulting in low bioavailability and short duration of...

Phosphorylated PEG-emulsifier: Powerful tool for development of zeta potential changing self-emulsifying drug delivery systems (SEDDS)

12. March 2020

Aim It was the aim of this study to synthesize a phosphorylated emulsifier possessing a PEG-linker for establishment of a...

Design of self-nanoemulsifying system to enhance absorption and bioavailability of poorly permeable Aliskiren hemi-fumarate

12. March 2020

The aim of this study was to develop self-nanoemulsifying system (SNES) to improve the oral bioavailability of Aliskiren hemi-fumarate (AF)....

Emulsifier