Freeze Drying

Abstract There is a growing demand in the subcutaneous delivery of monoclonal antibodies (mAbs) to reduce treatment burden for both...

Abstract Hygroscopicity poses a significant challenge in the formulation of pharmaceutical and nutraceutical products, as moisture absorption often leads to...

Abstract This study aims to develop the freeze-dried core–shell nanoparticles (nanocapsules; NCs) as an effective dosage form for improving the...

Abstract In this research, with the aim of improving the solubility and bioavailability of famotidine, the inclusion complex of famotidine...

Abstract Hypothesis During spray freeze drying (SFD), vitrification, recrystallization, and polymorphic transitions govern particle morphology and mechanical integrity. We hypothesize...

Abstract Extracellular vesicles (EVs) hold great promise as a novel therapeutic modality. While their use as certain formulations has been...

Spin freeze-drying (SFD) has emerged as a potential breakthrough in pharmaceutical lyophilization. It promises over 90 % reductions in cycle time...

Abstract Background: Despite the growing importance of polypeptide-based drugs in clinical therapy, studies investigating the stability of their freeze-dried formulations...

Abstract Background/Objectives: Dihydroquercetin (DHQ), also known as taxifolin, is a natural flavonoid which has anti-inflammatory and wound-healing biological effects. One...

Abstract Introduction: Formulation research benefits from high-throughput excipient screening methods, considering the ever-growing excipient space. We investigate the use of 384-well...