Freeze Drying

Abstract In this research, with the aim of improving the solubility and bioavailability of famotidine, the inclusion complex of famotidine...

Abstract Hypothesis During spray freeze drying (SFD), vitrification, recrystallization, and polymorphic transitions govern particle morphology and mechanical integrity. We hypothesize...

Abstract Extracellular vesicles (EVs) hold great promise as a novel therapeutic modality. While their use as certain formulations has been...

Spin freeze-drying (SFD) has emerged as a potential breakthrough in pharmaceutical lyophilization. It promises over 90 % reductions in cycle time...

Abstract Background: Despite the growing importance of polypeptide-based drugs in clinical therapy, studies investigating the stability of their freeze-dried formulations...

Abstract Background/Objectives: Dihydroquercetin (DHQ), also known as taxifolin, is a natural flavonoid which has anti-inflammatory and wound-healing biological effects. One...

Abstract Introduction: Formulation research benefits from high-throughput excipient screening methods, considering the ever-growing excipient space. We investigate the use of 384-well...

Freeze-drying Technology in Pharmaceutical and Biomedical Product Development Freeze-drying Technology in Pharmaceutical and Biomedical Product Development See the new book,...

Abstract Solid-state protein formulations are known to exhibit enhanced storage stability compared to their liquid dosage form counterparts. pH is...

A library of 16 lipid nanoparticle (LNP) formulations with orthogonally varying lipid molar ratios was designed and synthesized, using polyadenylic acid ...