Freeze Drying

Abstract Spray-freeze drying (SFD) is a promising drying technique for stabilizing RNA lipid nanoparticles (RNA-LNPs) by converting them into solid-state...

Abstract Inhalable messenger RNA (mRNA) therapeutics provide direct access to the respiratory tract but liquid mRNA-lipid nanoparticle (LNP) formulations often...

Abstract Lysine (Lys) is a nutritionally essential amino acid with a well-established parenteral safety record, yet its potential as a...

Abstract Capsule aperture geometry is a tunable design parameter that can markedly influence powder emission and aerosol dispersion in capsule-based...

Abstract To facilitate the development of protein depots for sustained delivery, this study optimized spray-dried formulations of a model antibody...

Abstract Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal...

Abstract There is a growing demand in the subcutaneous delivery of monoclonal antibodies (mAbs) to reduce treatment burden for both...

Abstract Hygroscopicity poses a significant challenge in the formulation of pharmaceutical and nutraceutical products, as moisture absorption often leads to...

Abstract This study aims to develop the freeze-dried core–shell nanoparticles (nanocapsules; NCs) as an effective dosage form for improving the...

Abstract In this research, with the aim of improving the solubility and bioavailability of famotidine, the inclusion complex of famotidine...