Freeze Drying

Abstract Introduction: Formulation research benefits from high-throughput excipient screening methods, considering the ever-growing excipient space. We investigate the use of 384-well...

Freeze-drying Technology in Pharmaceutical and Biomedical Product Development Freeze-drying Technology in Pharmaceutical and Biomedical Product Development See the new book,...

Abstract Solid-state protein formulations are known to exhibit enhanced storage stability compared to their liquid dosage form counterparts. pH is...

A library of 16 lipid nanoparticle (LNP) formulations with orthogonally varying lipid molar ratios was designed and synthesized, using polyadenylic acid ...

Freeze drying is a commonly used method for preserving probiotic bacteria and live biotherapeutic products. Before drying, the bacterial cells...

Abstract Freeze-drying of biopharmaceutical products is the method of choice in order to improve their stability and storage conditions. Such...

Abstract Background Process intensification is a major hurdle in pharmaceutical process scale-up. Solvent removal strategies have limited the effectiveness of...

Abstract Spray freeze-drying has emerged as a valid alternative to traditional spray drying to produce therapeutic dry microparticles. In particular,...

Messenger RNA (mRNA) lipid nanoparticles (LNPs) have emerged at the forefront during the COVID-19 vaccination campaign. Despite their tremendous success,...

Spray-drying is an inherently continuous and well-established industrial drying process. It can accelerate manufacturing of biopharmaceuticals and vaccine products, resulting...