Granulation

Binders or “granulating agents” are a critical formulation component in tablets made by direct compression, as well as dry, wet,...

Characterization of drug substances and excipients is a very important step at the preformulation phase of product development. Although testing...

This study aimed to compare the manufacturability and granule and tablet properties of green fluidized bed granulation (GFBG) and of...

Comprehensive understanding of an integrated continuous pharmaceutical technology was achieved in this study by a combining design of experiments and...

Despite significant advances in the research domain of continuous twin screw granulation, limited information is currently available on the impact of...

The U.S. Food and Drug Administration (FDA) emphasizes drug product development by Quality by Design (QbD). Critical material attributes (CMAs)...

Developing new pharmaceuticals is costly and time-consuming. New methods are always in demand for various stages of product development. Investing...

Pediatric formulations are strongly demanded from healthcare professionals and caregivers. Currently, solid dosage forms have been studied as pediatric preparations....

In pharmaceutical wet granulation, drying is a critical step in terms of energy and material consumption, whereas granule moisture content...

The binders povidone (Kollidon 30), copovidone (Kollidon VA64), hypromellose (Pharmacoat 606), and three types of hyprolose (HPC SSL‑SFP, HPC SSL,...