Granulation

The present work explores the pharmaceutical application of a novel seeded granulation to develop properties-improved, high drug-loaded, and sustained-release tablets using hydroxypropylcellulose...

In recent years, the interest in continuous manufacturing techniques, such as twin-screw wet granulation, has increased. However, the understanding of the...

Desmopressin acetate (DDAVP) is an oligopeptide indicated for the treatment of primary nocturnal enuresis, for example. The poor oral bioavailability...

Dose dumping is the major drawback of sustained release (SR) matrices. The current research aimed to develop the stable lipid-based...

Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have been...

Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for pharmaceutical industries, and the utilization is overgrowing due to...

Recently, the pharmaceutical industry has undergone changes in the production of solid oral dosages from traditional inefficient and expensive batch...

In twin screw melt granulation, granules are produced by passing mixtures of drug substances and polymeric binders through twin screw...

This chapter discusses different excipients traditionally used in granulation applications and the emerging high-functionality co-processed excipients that can improve granulation...

Continuous twin screw wet granulation is one of the key continuous manufacturing technologies that have gained significant interest in the...