Granulation

Granulation, a size enlargement technique to form agglomerates of primary particles, has proven to be effective in the production of...

Low dose micro-tablets with acceptable quality attributes, specifically content uniformity (CU), would not only enhance the dose flexibility in the...

The essence of Continuous Manufacturing (CM) resides in the fact that continuous process units are directly connected to each other...

Wetting is the initial stage of wet granulation processes during which the first contact between the powder and the liquid...

Twin screw granulation is becoming increasingly relevant due to its compact size, continuous and robust mode of operation, customizable design,...

Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow...

Powders are often granulated to improve their flow properties, content uniformity and processability. Dry granulation is increasingly becoming a preferred...

Solid fraction is a key intermediate product attribute which significantly affects the granule characteristics prepared in a roller compaction (RC)...

Moisture plays a major role in determining the attributes of granules prepared by fluidized bed granulation (FBG). Here, a semi-theoretical...

Two case studies were studied in a high shear wet granulator using a hydrophobic API and a hydrophilic excipient An...